DOLF Project Publications:

Changes in cytokine, filarial antigen, and DNA levels associated with adverse events following treatment of lymphatic filariasis.
BJ. Andersen, J. Kumar, K. Curtis, N. Sanuku, S. Satafan, CL. King, PU. Fischer, GJ. Weil
J. Infec. Dis. 217: 280- 287(2018)

Differential human gut microbiome assemblages during soil-transmitted helminth infections in Indonesia and Liberia.
BA. Rosa, T. Supali, L. Gankpala, Y. Djuardi, E. Sartono, Y. Zhou,K. Fischer, J. Martin, R.Tyagi, FK. Bolay, PU. Fischer, M. Yazdanbakhsh, M. Mitreva
Microbiome 6(33) (2018)

A multi-center field study of two point-of-care tests for circulating Wuchereria bancrofti antigenemia in Africa
CB. Chesnais, NP. Awaca-Uvon, FK. Bolay, M. Boussinesq, PU. Fischer, L. Gankpala, A. Meite, F. Missamou, SD. Pion, GJ. Weil
PLoS Negl.Trop. Dis. 11(9): 1-15 (2017)

Effect of 3 years of biannual mass drug administration with albendazole on lymphatic filariasis and soil-transmitted helminth infections: a community-based study in Republic of the Congo
SDS. Pion, CB. Chenaiz, GJ. Weil, PU. Fischer, F. Missamou, M. Boussinesq
Lancet Infect Dis. (2017)

Potential Value of Triple Drug Therapy with Ivermectin, Diethylcarbamazine, and Albendazole (IDA) to Accelerate Elimination of Lymphatic Filariasis and Onchocerciasis in Africa
PU. Fischer, CL. King, JA. Jacobson, GJ. Weil
PLoS Negl. Trop. Dis. 11(1): 1-10 (2017)

Effectiveness of a Triple-Drug Regimen for Global Elimination of Lymphatic Filariasis: A Modelling Study
MA. Irvine, WA. Stolk, ME. Smith, S. Subramanian, BK. Singh, GJ. Weil, E. Michael, TD. Hollingsworth
Lancet Infect. Dis. (2016)

Measurement of Circulating Filarial Antigen Levels in Human Blood with a Point-of-Care Test Strip and a Portable Spectrodensitometer
CB. Chesnais, J. Vlaminck, B. Kunyu-Shako, SD. Pion, NP. Awaca-Uvon, GJ. Weil, D. Mumba, M. Boussinesq
Am. J. Trop. Med. Hyg. 94(6):1324-1329 (2016)

Familial aggregation and heritability of Wuchereria bancrofti infection
CB. Chesnais, A. Sabbagh, SD. Pion, F. Missamou, A. Garcia, MJ. Boussinesq
JID 214:587-594 (2016)

Programmatic Use of Molecular Xenomonitoring at the Level of Evaluation Units to Assess Persistence of Lymphatic Filariasis in Sri Lanka
RU Rao, SD Samarasekera, KC Nagadavithana, MW Punchilewa, TDM Dassanayaka, Gamini PKD, E Ford, Udaya S, B Ranassinghe, RH Henderson, GJ Weil
PLoS Neglected Trop. Dis. 10(5):1-16 (2016)

Efficacy, Safety, and Pharmacokinetics of Coadministered Diethylcarbamazine, Albendazole, and Ivermectin for Treatment of Bancroftian Filariasis
EK. Thomsen, N. Sanuku, M. Baea, S. Satofan, E. Maki, B. Lombore, MS. Schmidt, PM. Siba, GJ. Weil, JW. Kazura, LL. Fleckenstein, CL. King
Clinical Infectious Diseases 62(3):334-41 (2016)

Community Attitudes Toward Mass Drug Administration for Control and Elimination of Neglected Tropical Diseases After the 2014 Outbreak of Ebola Virus Disease in Lofa County, Liberia
J. Bogus, L. Gankpala, K. Fischer, A. Krentel, GJ. Weil, PU. Fischer, K. Kollie, FK. Bolay
Am J Trop Med Hyg  2;94(3):497-503 (2016)

A Comparison of two tests for filarial antigenemia in areas in Sri Lanka and Indonesia with low-level persistence of lymphatic filariasis following mass drug administration
TC. Yahathugoda, T. Supali, RU. Rao, Y. Djuardi, D. Stefani, F. Pical, PU. Fischer, MM. Lloyd, PH. Premaratne, MV. Weerasooriya, GJ. Weil
Parasites & Vectors 8:369 (2015)

The Impact of Two Semi-annual Treatments with Albendazole Alone on Lymphatic Filariasis and Soil-Transmitted Helminth Infections: A Community-based Study in the Republic of Congo
SDS. Pion, CB. Chesnais, J. Bopda, F. Louya, PU. Fischer, AC. Majewski, GJ. Weil, M. Boussinesq, F. Missamou
Am J Trop Med Hyg 92(5):959-966 (2015)

Conventional parasitology and DNA-based diagnostic methods for onchocerciasis elimination programmes
MM. Lloyd, R. Gilbert, NT. Taha, GJ. Weil, A. Meite, IMM. Kouakou, PU. Fischer
Acta Trop 146:114-118 (2015)

Filarial Antigenemia and Loa loa Night Blood Microfilaremia in an Area Without Bancroftian Filariasis in the Democratic Republic of Congo
DK. Bakajika, MM. Nigo, JP. Lotsima, GA. Masikini, K. Fischer, MM. Lloyd, GJ. Weil, PU. Fischer
Am J. Trop. Med. Hyg. 91(6):1142-1148 (2014)

A case study in risk factors for LF in the Republic of Congo
CB. Chesnais, F. Missamou, SD. Pion, J. Bopda, F. Louya, AC. Majewski, PU. Fischer, GJ. Weil, M. Boussinesq
Parasites & Vectors 7:300 (2014)

A comprehensive assessment of lymphatic filariasis in Sri Lanka six years after cessation of mass drug administration
RU. Rao, KC. Nagodavithana, SD. Samarasekera, AD. Wijegunawardana, WDY. Premakumara, SN. Perera, S. Settinayake, JP. Miller, GJ. Weil
PLoS NTD 8(11):e3281 (November 2014)

Liquid chromatography-mass spectrometry analysis of diethylcarbamazine in human plasma for clinical pharmacokinetic studies
MS. Schmidt, CL. King, EK. Thomsen, PM. Siba, N. Sanuku, L. Fleckenstein
J Pharm. Biomed. Anal. 98:307-10 (September 2014)

Exploring the potential of flubendazole in filariasis control: Evaluation of the systemic exposure for different pharmaceutical preparations
L. Ceballos, C. Mackenzie, T. Geary, L. Alvarez, C. Lanusse
PLoS NTD 8(5):e2838 (May 2014)

Integrated school-based surveillance for soil-transmitted helminth infections and lymphatic filariasis in Gampaha District, Sri Lanka
S. Gunawardena, NK. Gunawardena, G. Kahathuduwa, ND. Karunaweera, NR. de Silva, UB. Ranasinghe, SD. Samarrasekara, KC. Nagodavithana, RU. Rao, MP. Rebollo, GJ. Weil
Am J. Trop. Med. Hyg. 90(4):661-666 (2014)

Short report: Semi-quantitative scoring of an immunochromatographic test for circulating filarial antigen
CB. Chesnais, F. Missamou, SDS. Pion, J. Bopda, F. Louya, AC. Majewski, GJ. Weil, M. Boussinesq
Am. J. Trop. Med. Hyg. 89(5):916-918 (2013)

A review of factors that influence individual compliance with mass drug administration for elimination of lymphatic filariasis
A. Krentel, PU. Fischer, GJ. Weil
PLoS NTD 7(11):e2447 (November 2013)

Laboratory and field evaluation of a new rapid test for detecting Wuchereria bancrofti antigen in human blood
GJ. Weil, KC. Curtis, L. Fakoli, K. Fischer, L. Gankpala, PJ. Lammie, AC. Majewski, S. Pelletreau, KY. Won, FK. Bolay, PU. Fischer
Am. J. Trop. Med. Hyg. 89(1):11-15 (2013)

Modeling the impact and costs of semiannual mass drug administration for accelerated elimination of lymphatic filariasis
WA. Stolk, QA. ten Bosch, SJ. de Vlas, PU. Fischer, GJ. Weil, AS. Goldman
PLoS NTD 7(1):e1984 (January 2013)

A review of flubendazole and its potential as a macrofilariacide
C. Mackenzie
A report submitted to Dr. Gary Weil (PI DOLF) – a study supported by the Bill & Melinda Gates Foundation

Progress and challenges in the discovery of macrofilaricidal drugs
TG. Geary, CD. Mackenzie
Expert Rev. Anti Infect. Ther. 9(8):681-695 (2011)

Flubendazole: a candidate macrofilaricide for lymphatic filariasis and onchocerciasis field programs
CD. Mackenzie, TG. Geary
Expert Rev. Anti Infect. Ther. 9(5):497-501 (2011)


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